Dr. Marcy Zenobi-Wong is a full Professor of Tissue Engineering and Biofabrication at ETH Zürich, Switzerland.    She obtained her PhD from Stanford University and then did a post-doctoral fellowship in the Orthopaedic Research Laboratories, University of Michigan.  In 2012, she moved to the Department of Health Sciences & Technology at ETH Zürich.  The Zenobi-Wong research group is focused on the development of advanced biomaterials for tissue regeneration using biofabrication technologies including bioprinting, two-photon polymerization, casting and electrospinning.  Dr. Zenobi-Wong is the author of over 120 peer-reviewed publications and co-inventor on four licensed patents.  She has held leadership roles at the Swiss Society for Biomaterials and Regenerative Medicine,  the International Society of Biofabrication (ISBF) and is past director of the Institute for Biomechanics, ETH Zürich.   She serves on the editorial board for Biofabrication and Advanced Healthcare Materials.

Topic title: Filamented Light Biofabrication for Tissue Engineering of Tendon and Muscle

Abstract:

The development of functional engineered tissues can be greatly enhanced through the use of scaffolds which contain cell-instructive cues.  Materials which are composed of individual microgels are bettered positioned to provide these important cell signals compared to bulk materials.  Microgels can promote biological processes such as cell migration, cell viability, and cell proliferation due to the increased diffusional properties afforded by the natural void spaces.  Microgels can also direct the spatial deposition of extracellular matrix and cell morphology.  I will discuss how microgels can be incorporated into different strategies such as extrusion bioprinting and filamented light Biofabrication using tendons and muscle as examples