姜楠，教授、博士生导师，国家海外高层次青年人才、四川省天府峨眉青年科技人才，教育部、科技部、国家留学基金委、国家自然科学基金、中国博士后基金和省市科技项目评审专家，四川大学“双百”人才，曾在哈佛大学、帝国理工学院和斯坦福大学从事研究和访问。现就职于四川大学华西基础医学与法医学院 “生物打印与医用传感”研究团队负责人，中国生物材料学会材料生物力学与力学生物学分会委员, 中国生物医学工程学会传感技术分会青年委员。近年来发表高水平论文60余篇，其中在Matter、Adv. Mater.(2篇)、Adv. Funct. Mater.(4篇)、Trend Biotechnol、ACS Nano、Adv. Sci.等国际期刊上发表第一作者和通讯作者论文（含共同）40余篇，期刊封面论文5篇、ESI高被引论文1篇、热点论文1篇， H指数28。美国CNN、哈佛大学Harvard Gazette，麻省理工科技评论DeepTech，英国BBC网站等十余家国际主流媒体报道。荣获国际可穿戴计算顶级会议（ISWC） “Honorable Mentions” 奖、国际先进材料学会（IAAM）“Young Scientist Medal”奖、哈佛医学院 “Excellence in Innovation”奖以及四川大学“优秀科研人才”奖。担任Science合作期刊Advanced Devices&Instrumentation副主编、The Innovation期刊青年编委、Advanced Fiber Materials期刊青年编委、Biosensors期刊专题编辑、期刊Micromachines客座编辑，并兼任Adv. Mater、ACS Nano、ACS Cent. Sci.等30余本国际权威期刊通讯审稿人。主持国家自然科学基金、省人才基金等多项科研项目。荣获全国大学生基础医学创新研究暨实验设计论坛全国金奖和四川省国际互联网+大学生创新创业大赛金奖优秀指导教师。

Topic title: Manufacturing flexible fiber-optic chemical sensors for disease dynamic monitoring

Abstract：

Flexible fiber-optic chemical sensors that can selectively reflect biochemical marker levels in biological tissues have been widely used in biomedical applications. However, absorption, scattering, reflection, and transmission will occur during light transmission within biological tissues, thus significantly reducing light transmission efficiency and depth. Therefore, improving the light transmission efficiency in biological tissues is an important step for optical sensing in deep biological tissues. Fiber-optic sensing technology can enhance the light transmission efficiency in deep tissues based on the principle of total internal reflection. Considering the poor matching between traditional optical fiber materials and flexible biological tissues, we have manufactured flexible optical chemical fiber sensors for the dynamic monitoring of biomarkers in biological tissues. To improve the accuracy of diagnosis, we have further manufactured multiplexed fiber-optic chemical sensors to dynamically monitor multiple physiological and biomarkers in the brain, providing an important research basis for intraoperative and postoperative monitoring of patients with traumatic brain injury.