周长春，四川大学生物医学工程学院、国家生物医学材料工程技术研究中心，研究员，工学博士，博士生导师，中共党员，学院博士一支部书记。中国生物材料学会会员、中国机械工程学会高级会员、中国生物材料学会先进制造分会委员、中国医药生物技术协会3D打印技术分会委员、3D打印技术分会材料学组组长、中国机械工程学会生物制造工程分会委员、全国增材制造标准化技术委员会委员、SCI期刊Bio-design and Manufacturing (ISSN2096-5524)副主编。长期从事生物材料、人工器官3D打印制造研究。先后主持或参与了包括欧盟“Horizon 2020”、科技部重点研发专项、国家自然基金、四川省科技厅、经信委、成都市科技局等10多项科研项目。以第一作者或通讯作者共发表论文SCI论文100多篇；申请专利36项，授权20多项；指导学生获大创、互联网加等项目省部级金奖5项，国家级金奖2项。

Biography: Changchun Zhou is a full professor of Sichuan University, he received a PhD degree from Sichuan University in 2011, he once been a joint PhD student at the University of Washington (2008-2009) and the University of Texas at Austin (2009-2010). He is currently a member of China society of biomaterials, member of the biofabrication branch of China mechanical engineering society (2017-). He is an Associate editor of SCI Journal “Bio-Design and Manufacturing”. His research interests cover Biomaterials and artificial organs; 3D bioprinting or biofabrication of bone tissue scaffolds. He has published more than 100 scientific papers. He has applied more than 36 Chinese national patents, among of which 20 patents have been authorized.

Topic title: Biofabrication of multiple biomaterials for customized bone tissue defect repair

Abstract:

In recent years, biofabrication has been widely studied and applied in regenerative medicine. Our research group focused on the printing performance of their respective biomaterials, including their physical and chemical properties, as well as their application in different personalized tissue repair scenarios. With the advancement of 3D printing technology, human tissue organs, bone tissue scaffolds, can be accurately fabricated. Complex inner micro structures and high levels of outer shape can be designed and manufactured according to the 3D printing strategy. As an essential part of the human motion system, bone plays the role of locomotion, supporting, and protecting the body. Bone repair materials not only require a customized shape to match the defect but also need a specific porous structure to modulate their biological activity. Our research focused on utilized 3D printing technology to prepare a biomimetic porous architecture scaffold for investigating artificial tissue organs.

Fig. 1. 3D printing technology can flexibly use to fabricate polymers, metals, ceramics, and their composite products for personalized artificial organ and tissue engineering applications.

Keywords: 3D printing; Bioceramics; Titanium implants; Polymer and hydrogels.

References:

[1] Boqing Zhang, Xingyu Gui, Ping et.al Three-dimensional printing of large-scale, high-resolution bioceramics with micro-nano inner porosity and customized surface characterization design for bone regeneration. ACS Appl. Mater. Interfaces 2022, 14, 7, 8804–8815.

[2] Huan Sun, Chenxi Zhang, Boqing Zhang, et.al. 3D printed calcium phosphate scaffolds with controlled release of osteogenic drugs for bone regeneration. Chemical Engineering Journal 427 (2022) 130961-17.

[2] Xuan Pei, Linnan Wang, Changchun Zhou*, et.al. Ti6Al4V orthopedic implant with biomimetic heterogeneous structure via 3D printing for improving osteogenesis. Materials & Design 221 (2022) 110964.