马少华
清华大学深圳国际研究生院
Dr. Shaohua Ma received his B.Eng from the Department of Polymer Materials and Engineering at Sun Yat-sen University in 2009, and Ph.D. from the Department of Chemistry at the University of Cambridge in 2013. He did the postdoctoral training at the University of Oxford in 2013 – 2017 before joining Tsinghua University in 2017, first as an assistant professor and then associate professor (core-PI) at Tsinghua-Berkeley Shenzhen Institute (TBSI). He is now an associate professor with tenure at Institute of Biopharmaceutical and Health Engineering (iBHE), Tsinghua Shenzhen International Graduate School (SIGS). His research interests include intelligent microfluidics, organoids and stem cell engineering, organs-on-a-chip, 3D bioprinting, and has contributed over 40 papers as the first and corresponding authors to these fields.
Topic title: Organoid printing for precision cancer medicine and regeneration and repair
Abstract:
Organoids are three-dimensional micro-replicas of human organs in of human organs in either physiological or pathological states. Organoids are expected to provide personalised drug treatment choices by assessing drug efficacy and toxicity in efficacy and toxicity in vitro, or augment regenerative therapy by exploiting their colonized of their colonised stem cell-like capacities. Here we report a bead-jet bead-printing method that is suitable for both reproducible and high-throughput high-throughput formulation and patterning of organoids. It allows organoid printing in both parallel culture chambers, such as 96-well plates, and irregular wounds. It also has significant translation potential by providing an automated tool for organoid and living bead printing.