Jun Yin received the Ph.D. degree in mechanical engineering of Clemson University in 2011. From 2011 to 2013, he was a post-doctoral scholar with the School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Since 2014, he has been a Professor with the School of Mechanical Engineering, Zhejiang University. His main research interests are focused on 3D bioprinting, including the design and modeling of biofabrication processes, synthesis and application of biomaterials, and biomechanics during bioprinting.

Topic title: Continuous DLP printing of multiply cells using yield stress fluid bioink

Abstract:

In conventional digital light process (DLP) printing, the higher printing resolution generally leads to a low printing efficiency, while the multiple prolonged UV light exposure affects the activity of cells encapsulated in the hydrogel-based bioinks. Based on the precise curing condition controlling, a continuous DLP printing method was developed. Also, dynamic support bath assisted DLP printing method using yield stress fluid was proposed. this printing method achieved the DLP printing of extremely soft cell-laden bioinks (Young’s modulus of 4.3 KPa) into 3D complex constructs with excellent biological functionality. More importantly, assisted by the magnetic field, continuous DLP printing of multiply cells was achieved. This high-shape fidelity and high-efficiency DLP method can significantly improve the activity of cells in the process of making biological tissue engineering scaffolds and is more conducive to the growth of cells in the scaffold.